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Index > Protein center > NFATC1(Gene name) > Bovine
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  • NFATC1 (Gene name),
  • Nuclear factor of activated T-cells, cytoplasmic 1 (Protein name ),  NFAC1_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    NFATC1;
    Protein name:
    Nuclear factor of activated T-cells, cytoplasmic 1(NF-ATc1;NFATc1);
    Alternative:
    NFAT transcription complex cytosolic component(NF-ATc;NFATc);
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Member of the multicomponent NFATC transcription complex that consists of at least two components, a pre-existing cytoplasmic component NFATC2 and an inducible nuclear component NFATC1. Other members such as NFATC4, NFATC3 or members of the activating protein-1 family, MAF, GATA4 and Cbp/p300 can also bind the complex. NFATC proteins bind to DNA as monomers.
    Function:
    Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells.
    Subcellular Location:
    Cytoplasm Nucleus Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.
    Protein Attributes:
    Sequence length:
    803
    Sequence:
    50:
    MTGLEEDQEF | DFDFLFEFNQ | SDEGAVAAPA | EHYGYAAPGL | GAGLPLSAAH | 
    100:
    PSLPAPCHDL | QSSAAGVSAV | GYGGTVDSGP | SGYFLSSGGI | RPNGAPALES | 
    150:
    PRIEITSYLG | LHHNSSQFLH | EVDVEDVLPK | RSPSTATLNL | PSLEAYRDPS | 
    200:
    CLSPASSLSS | RSCNSEASSY | ESSFSYPYAS | PQTSPWQSPC | VSPKTTDPEE | 
    250:
    GFARGLGACG | LLGSPRHSPS | TSPRTSVTEE | SWLGARTSRP | SSPCNKRKYG | 
    300:
    LNGRQLSCSP | HPSPTPSPQG | SPRVSVTDDT | WLGNTTQYTS | SAIVAAINAL | 
    350:
    STDSSLDLGD | GVPVKARKTT | LDHSPAVALK | VEPAGEDLGT | TPPTPDFQPE | 
    400:
    EFAAFQHIRK | GAFCDQYLSV | PQHPYPWARP | RSPASYTSPS | LPALDWQLPS | 
    450:
    HSGPYELRIE | VQPKSHHRAH | YETEGSRGAV | KASAGGHPSV | QLHGYVESEP | 
    500:
    LTLQLFIGTA | DDRLLRPHAF | YQVHRITGKT | VSTASHEAVV | CSTKVLEIPL | 
    550:
    LPENNMRATI | DCAGILKLRN | SDIELRKGET | DIGRKNTRVR | LVFRVHIPQP | 
    600:
    NGRTLSLQVA | SNPIECSQRS | AQELPLVEKQ | SAASGPVLGG | KRMVLSGHNF | 
    650:
    LQDSKVIFVE | KAPDGHHIWE | MEAKTEGDLC | KPNSLVVEIP | PFRNQRITSP | 
    700:
    VQVNFYVCNG | KRKRSQYQHF | TYLPANVPII | KTEPSDDYEP | ALTCGPMSQG | 
    750:
    LSPLPKPCYG | QPLALPPDPG | ACLMPGFPPR | PQGSASPELH | DLSCAPYGSA | 
    800:
    TAGPGHSPLG | LPRPVGGVLA | SQEAPRPSGV | PPGPPQPPPP | TLLQPQVSPT | 
    803:
    SSG
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine NF-ATc1
    Cat.:
    E1519h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine NF-ATc1
    Cat.:
    E1519m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine NF-ATc1
    Cat.:
    E1519b
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Bovine NF-ATc1
    Cat.:
    E1519p
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine NF-ATc1
    Cat.:
    U1519b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine NF-ATc1
    Cat.:
    U1519m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine NF-ATc1
    Cat.:
    U1519p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine NF-ATc1
    Cat.:
    U1519h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine NF-ATc1
    Cat.:
    P1519Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine NF-ATc1
    Cat.:
    P1519Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine NF-ATc1
    Polyclonal Antibody for Bovine NF-ATc1
    Monoclonal Antibody for Bovine NF-ATc1
    Monoclonal Antibody for Bovine NF-ATc1
    Monoclonal Antibody for Bovine NF-ATc1
    Monoclonal Antibody for Bovine NF-ATc1
    Protein for Bovine NF-ATc1
    Protein for Bovine NF-ATc1
    Protein for Bovine NF-ATc1
    Protein for Bovine NF-ATc1

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    References
    1. 1.
      "The genome sequence of taurine cattle: a window to ruminant biology and evolution."
      The bovine genome sequencing and analysis consortium
      Science324:522-528(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Hereford.
    2. 2.
      "NF-AT components define a family of transcription factors targeted in T-cell activation."
      Northrop J.P. , Ho S.N. , Chen L. , Thomas D.J. , Timmerman L.A. , Nolan G.P. , Admon A. , Crabtree G.R.
      Nature369:497-502(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 415-430; 432-441; 518-534; 536-545; 554-560 AND 612-615
      tissue: Thymus.
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